David Willey will miss England's three-match one-day international series against West Indies in the Caribbean next month.
The Yorkshire allrounder had surgery on his left shoulder on Friday to further assess the injury he sustained while bowling in the third ODI against India last month. He has suffered a partial tear of a tendon and will be out of action until April.
Willey will be replaced in the England squad by Middlesex seamer Steven Finn, who is currently playing in the Pakistan Super League in the UAE.
England fly to the Caribbean next Wednesday, where they play two warm-up matches and three ODIs against West Indies.
Willey, lightly used throughout the one-day series against India - bowling over 13 overs in three matches - was only able to manage two overs in the final ODI in Kolkata before leaving the field.
He has only completed a full 10-over spell in seven of his 25 ODIs, with his captain, Eoin Morgan, seemingly reluctant to use him beyond his threat swinging the new ball.
He remained behind in Kolkata for scans when the rest of the squad travelled to Kanpur for a three-match T20 series, with England Cricket tweeting that "a scan didn't show up significant damage to his left shoulder".
That initial diagnosis proved to be overly optimistic and he returned home for an operation, the extent of which has now been revealed.
Willey's latest injury also threatens to disrupt his involvement at the start of Yorkshire's season and will not help him claim a place in the Championship side for a county where Ryan Sidebottom, a fellow left-armer, shows few signs of deterioration at 39 and, at the other end of the age scale, Matt Fisher, if he can shake off the injury worries that have curtailed his involvement in the England Under-19 tour of India, is ambitious to prove himself England's brightest fast bowling prospect.