Amy Louise Gerard has been missing since early Friday after she was last seen standing outside an Irish pub in Puerto de la Cruz.
Amy Louise Gerard, 28, was last seen standing outside Irish Molly Malone's in Puerto de la Cruz at around 12.20am on Friday.
Originally from Grimsby, Lincolnshire, Ms Gerard works as an animal trainer at Tenerife's Loro Parque theme park.
The Foreign and Commonwealth Office has confirmed it is assisting the family of a British woman in Tenerife.
Ms Gerard's family members, including her mother Julie and sister Chloe, are believed to have flown out to the Spanish island.
Spain's Policia Nacional has released a missing poster for the young woman.
It reads: "Age 28, British, approx 177cm tall with curly blonde hair and blue eyes.
"Last seen outside Irish bar Molly Malone in Puerto de la Cruz, approx. 12.20am 30/11/18 (late Thursday evening)."
Ms Gerard's family and friends have been sharing an appeal to find her on social media.
Her sister Chloe tweeted: "My sister has been missing since Thursday night! Please help find her. Last seen in puerto de la Cruz, Tenerife. #MissingPerson #Tenerife".
Her best friend Tara Dudley also shared the missing poster on Instagram.
Ms Dudley asked the public to "please engrave this girl's face in your brain" and added that her friend had been wearing black Ugg boots, jeans and a jacket on the night she vanished.
She added that "there are a lot of people worried about her whereabouts".
Ms Gerard describes herself as a killer whale trainer on social media after studying animal behaviour science at the University of Lincoln.
She also spent time working as a marine mammal trainer in France and subsequently Mexico before moving to Tenerife in 2016.