A 78-year-old man has been charged with rape and four counts of indecent assault relating to incidents at hospitals in Berkshire, including Stoke Mandeville, in the 1970s and 1980s.
Michael Salmon, from Wood Green in Hampshire, was arrested on Wednesday and charged by Thames Valley Police.
He was held under Operation Yewtree - set up in the wake of the Jimmy Savile sex abuse claims.
His arrest falls under a strand of the operation which is unrelated to Savile.
A Thames Valley Police spokesman said: "The charges relate to incidents involving four victims from 1972 to 1985 at various hospitals in the Aylesbury area, including Stoke Mandeville Hospital."
Mr Salmon has been bailed to appear at Aylesbury Magistrates' Court, in Berkshire, on 17 December.
Operation Yewtree was launched after claims of sexual abuse were made against the former BBC radio DJ and television presenter, Savile - who died aged 84 in 2011.
It has three strands - one is looking specifically at the actions of Savile, while the second strand concerns allegations against "Savile and others".
The third strand relates to allegations against other people unconnected to the Savile investigation.