The disgraced Oscar winner will appear in a thriller which was filmed two-years-ago, but will be released in cinemas next month.
The Oscar winner was one of the first stars to be accused of sexual misconduct in the wake of the Harvey Weinstein scandal.
He has faced multiple accusations of sexual harassment since actor Anthony Rapp said the star had made a sexual advance toward him in 1985, when he was just 14 years old and Spacey was 26.
The former artistic director of the Old Vic was also investigated by the Metropolitan Police over three allegations of sexual assault in London - two in 2005 and one in 2008.
The 58-year-old actor has not been arrested or charged with any crime.
In his big-screen comeback in the Billionaire Boys Club, Spacey will play the role of Ron Levin - a real-life con artist.
The film also stars Taron Egerton, Emma Roberts, Suki Waterhouse and Ansel Elgort.
The thriller was filmed two-years-ago, but will be released in cinemas in July.
It focuses on a get-rich-quick scam which preyed on the families of wealthy Harvard school boys in Los Angeles in the early 1980s.
A sexual assault charge against Spacey is being reviewed by prosecutors in Los Angeles.